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Symbol
Name
ID
Sgpl1
sphingosine phosphate lyase 1
MGI:1261415
Phenotype annotations related to endocrine/exocrine glands
Darker colors indicate more annotations
Human Phenotypes
Adrenal insufficiency
Hypothyroidism
Hypogonadism
Disease(s) Associated with SGPL1
nephrotic syndrome type 14

Mouse Phenotypes
thymus cortex hypoplasia
thymus medulla hyperplasia
thymus hypoplasia
increased thymocyte number
abnormal ovary morphology
absent corpus luteum
decreased tertiary ovarian follicle number
decreased theca cell number
small ovary
abnormal testis morphology
abnormal testis cord formation
decreased Leydig cell number
small testis
Availability Mouse Genotype
Sgpl1Gt(OST58278)Lex/Sgpl1Gt(OST58278)Lex
Sgpl1Gt(ROSA)78Sor/Sgpl1Gt(ROSA)78Sor
Sgpl1tm1.1(KOMP)Vlcg/Sgpl1+
Actbtm4(cre/ERT2)Npa/Actb+
Sgpl1tm1.1Npa/Sgpl1tm1.1Npa  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory